Data Scientist Jobs in South Dakota, United States

81 jobs available

Find Data Scientist opportunities in South Dakota, United States. Browse 81 open positions from top employers in the area.

Showing 20 of 81 jobs

Data Scientist

Sterling Computers

North Sioux City, South Dakota, United States Full-time On-site

Data Science team at Sterling Computers builds advanced data products and models to improve operational efficiency and financial reporting. The Data Scientist designs, develops, and deploys complex models, creates data pipelines, and provides predictive tools to support sales and cross‑functional teams.

Last seen Oct 23, 2026
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Principal Data Scientist

o9 Solutions

South Dakota, United States Full-time Remote $161,304 - $221,792

We are seeking an experienced Principal Supply Chain Data Scientist with deep technical mastery in time series forecasting and predictive analytics to join our US Delivery & Solutions team. In this role, you will lead the customer implementations including the architecture, design/development, and deployment of state-of-the-art forecasting and demand sensing algorithms that drive multi-billion-dollar supply chain decisions for Fortune 500 clients.

Last seen Oct 14, 2026
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Sr. Data Scientist - Process Modeling

Amgen

Sioux Falls, South Dakota, United States Full-time Remote $134,168 - $181,522

In this vital role you will join the Digital Process and Systems Analysis group within Process Development plays a key role in providing data infrastructure, platforms, and analytics to support engineering teams across our network, ensuring […] This position is part of a team advancing biologics drug-substance modeling and the digitization of tech-transfer workflows. As new modeling capabilities are developed and information is parameterized, opportunities abound to deploy modeling tools to enab

Last seen Oct 23, 2026
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Senior Data Scientist - Clinical Informatics (Analytics Enablement)

CVS Health

South Dakota, United States Full-time Remote $83,430 - $222,480

As a Senior Data Scientist - Clinical Informatics (Analytics Enablement) , you are tasked with activating CVS Health's clinical data repository to improve outcomes across multiple lines of business and use cases. You will serve as a bridge between clinical data assets and the analysts, data scientists, and business partners who consume them—ensuring data is accessible, well-documented, fit for purpose, and aligned with clinical and regulatory standards.

Last seen Oct 12, 2026
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R&D Research- Associate Scientist

Medgene Labs

Brookings, South Dakota, United States Full-time On-site

R&D team at Medgene Labs develops immunological products to protect livestock. The Associate Scientist conducts and designs immunological assays, processes clinical samples, and performs data analysis to support vaccine research across multiple species.

Last seen Oct 19, 2026
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Medical Laboratory Technician / Scientist

Regional Health

Sturgis, South Dakota, United States Full-time On-site $24 - $40 / hour

STH Laboratory at Monument Health provides essential diagnostic testing to support patient care. The role performs specimen collection, prepares samples, conducts routine and complex lab tests, ensures quality and calibration of equipment, and reports results to physicians while supervising new staff.

Last seen Oct 16, 2026
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Medical Laboratory Technician or Scientist

Regional Health

Spearfish, South Dakota, United States Full-time

10th St Laboratory at Monument Health provides essential diagnostic services to the Spearfish community. The team performs routine and complex laboratory tests, ensures specimen integrity, and supports quality assurance and equipment calibration.

Last seen Oct 23, 2026
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Medical Laboratory Scientist or Tech

Avera Health

Britton, South Dakota, United States Full-time On-site

Marshall County Healthcare Center seeks a Medical Laboratory Scientist or Technician to support patient care through high‑volume laboratory testing. The role collects, processes, and analyzes blood samples, ensures quality assurance, and troubleshoots instrument and methodological issues.

Last seen Oct 23, 2026
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Medical Laboratory Scientist

Avera Health

Yankton, South Dakota, United States Part-time $24 - $44 / hour

Location: Avera Sacred Heart Hospital Worker Type: Regular Work Shift: Primarily evenings with rotating weekends and holidays (United States of America) Pay Range: The pay range for this position is listed below. Actual pay rate dependent upon experience.

Last seen Oct 23, 2026
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Medical Laboratory Scientist

Avera Health

Aberdeen, South Dakota, United States Full-time $24 - $44 / hour

Location: Avera Aberdeen Family Physicians Worker Type: Regular Work Shift: Primarily days with rotating weekends and holidays (United States of America) Pay Range: The pay range for this position is listed below. Actual pay rate dependent upon experience.

Last seen Oct 23, 2026
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Medical Laboratory Technician/ Scientist

Sanford Health

Sioux Falls, South Dakota, United States Full-time $25 - $44 / hour

Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland. 

 Work Shift: Varies (United States of America)

 Scheduled Weekly Hours: 40

 Compensation: Salary Range: $25 - $44

sign on bonus available

 Union Position: No

 Department Details Summary Responsible for pre-analytical, analytical, and post-analytic

Last seen Oct 23, 2026
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Medical Laboratory Technician/ Scientist

Sanford Health

Sioux Falls, South Dakota, United States Full-time $25 - $44 / hour

Responsible for pre-analytical, analytical, and post-analytical phases of testing.

Last seen Oct 23, 2026
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Senior Clinical Scientist

Aurion Biotech Inc.

South Dakota, United States Full-time Remote $158,000 - $188,000

Aurion Biotech is seeking a highly motivated and experienced Senior Clinical Scientist to join the Clinical Development organization. Reporting to the Director of Clinical Science, this individual will serve as the scientific lead for one or more ophthalmology clinical programs and will play a critical role in the design, execution, analysis, and interpretation of clinical trials.

Last seen Oct 13, 2026
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Medical Laboratory Technician/Scientist

Avera Health

Mitchell, South Dakota, United States Full-time $24 - $44 / hour

Performs a variety of clinical laboratory tests, procedures and related duties. Utilizes scientific principles as well as technical, procedural, and problem-solving aptitudes for day-to-day laboratory technical operations, quality control, quality assurance, procedure/instrument maintenance and corrective action, test result correlation, and clinical laboratory related continuing education.

Last seen Oct 23, 2026
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Medical Laboratory Scientist/ Technician

Sanford Health

Aberdeen, South Dakota, United States Full-time $25 - $44 / hour

Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland. 

 Work Shift: 10 Hours - Varied Shifts (United States of America)

 Scheduled Weekly Hours: 36

 Compensation: Salary Range: $25 - $44

sign on bonus available

 Union Position: No

 Department Details 10 hour varied shifts, no call, every fourth weeken

Last seen Oct 23, 2026
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Quality Control Associate Scientist

Medgene Labs

Brookings, South Dakota, United States Full-time

The Quality Control Associate Scientist, as a member of the Manufacturing Team, ensures reliable and accurate test results on products in compliance with regulatory requirements for USDA product release.

Last seen Oct 23, 2026
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Senior Scientist, Analytical Science & Technology

Aurion Biotech Inc.

South Dakota, United States Full-time Remote $140,000 - $155,000

This position is a unique and exciting opportunity to join a growing team of passionate professionals at the forefront of cell therapy innovation in ophthalmology. As a Senior Scientist, AS&T you will play a critical role in accomplishing our mission.

Last seen Oct 23, 2026
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Variant Assessment Scientist I– Cardiology (REMOTE, USA)

Tempus

South Dakota, United States Full-time Remote $100,000 - $112,000

Responsibilities include variant analysis of diagnostic molecular genetic test results; evaluation of published literature, clinical data and review of both functional and in silico data to provide accurate, thorough, and thoughtful clinical interpretation of results. Write research articles in collaboration with other medical professionals and colleagues outside and inside the organization, if data is relevant to the scientific community.

Last seen Oct 21, 2026
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Medical Laboratory Scientist - SN | Core Lab

Sanford Health

Sioux Falls, South Dakota, United States Full-time On-site $25 - $44 / hour

Responsible for pre-analytical, analytical, and post-analytical phases of testing. Follows standard operating procedures and ensures laboratory safety, quality and regulatory requirements are met.

Last seen Oct 15, 2026
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Medical Laboratory Scientist/ Technician- Straight Nights

Sanford Health

Sioux Falls, South Dakota, United States Full-time $25 - $44 / hour

Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland. 

 Work Shift: 8 Hours - Night Shifts (United States of America)

 Scheduled Weekly Hours: 40

 Compensation: Salary Range: $25 - $44

sign on bonus available

 Union Position: No

 Department Details Sign on Bonus Available Straight Night Shift with shi

Last seen Oct 23, 2026
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Data Scientist Jobs in South Dakota: FAQ

How many Data Scientist jobs in South Dakota are open right now?

81 Data Scientist jobs in South Dakota are live on NextGig, all seen active within the last 45 days. The list refreshes daily as new roles are posted and filled ones drop off.

Which companies are hiring for Data Scientist jobs in South Dakota?

Employers with current openings include Sterling Computers, o9 Solutions, Amgen, CVS Health, Medgene Labs, Regional Health, and others. Every listing links straight to the employer's application page.

What do Data Scientist jobs in South Dakota pay?

15 of the 20 newest listings disclose pay, for example $161,304 - $221,792 at o9 Solutions, $134,168 - $181,522 at Amgen, $83,430 - $222,480 at CVS Health. Open a listing for the full compensation details.

Are any of these roles remote?

Of the 20 newest listings on this page, 6 are remote. The work model is shown on each job card.