Data Scientist Jobs in South Dakota, United States

58 jobs available

Find Data Scientist opportunities in South Dakota, United States. Browse 58 open positions from top employers in the area.

Showing 20 of 58 jobs

Data Scientist

Sterling Computers

North Sioux City, SD, US Full-time On-site

Data Science team at Sterling Computers builds advanced data products and models to improve operational efficiency and financial reporting. The Data Scientist designs, develops, and deploys complex models, creates data pipelines, and provides predictive tools to support sales and cross‑functional teams.

Last seen Sep 3, 2026
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Lead Data Scientist

Humana

Remote South Dakota Full-time Remote $156,500 - $215,300 / year

The Lead Data Scientist at Humana transforms high volumes of complex data into advanced analytic solutions using mathematics, statistics, modeling, business analysis, and technology. Day-to-day work includes developing and maintaining structured and unstructured data sets, creating reports, projections, models, and presentations to support business strategy, and advising executives on functional strategies.

Last seen Aug 24, 2026
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Senior Data Scientist - AI Services and Platforms

Highmark Health and Allegheny Health Network

SD, United States Full-time $102,700 - $164,600 / year

AI + Data Services and Platforms (AIPS) at Highmark Health drives generative and predictive AI solutions for enterprise stakeholders. The Senior Data Scientist designs end‑to‑end AI/ML pipelines, evaluates models with Responsible AI principles, and translates insights into business impact across cross‑functional teams.

Last seen Sep 2, 2026
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Sr. Data Scientist, Applied AI/ML

CrowdStrike

USA - Remote, SD Full-time Remote $140,000 - $215,000 / year

CrowdStrike's NGSIEM Agentic AI team is seeking a Senior Data Scientist to design, build, and deploy advanced AI systems that analyze and prioritize millions of security events per second. Day-to-day work includes leading architecture for large-scale retrieval, ranking, vector search, RAG, and anomaly detection; owning end-to-end ML pipelines; driving cross-functional AI initiatives; and mentoring junior scientists.

Last seen Sep 3, 2026
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Lead Director, Data Science - Clinical AI

CVS Health

Work At Home-South Dakota Full-time Remote $64,890 - $173,040 / year

CVS/Oak Street Health’s Decision Sciences team is hiring a Data Scientist to deliver data-driven solutions that optimize Oak Street Health’s care model and improve patient outcomes. Day-to-day, you will design and execute prospective study designs, ROI assessments, and clinical program evaluations; create statistical analysis plans with stakeholders; analyze large structured and unstructured datasets; and present findings to diverse audiences.

Last seen Sep 3, 2026
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Medical Laboratory Scientist

Avera Health

Gettysburg, SD Full-time $29 - $44 / hour

Medical Laboratory Scientist at Avera Gettysburg Hospital in Gettysburg, SD, performing clinical laboratory tests and supporting day-to-day lab operations, quality control, and corrective action. The role involves correlating results, alerting staff to abnormal findings, communicating data across departments, and providing technical guidance and training to team members.

Last seen Aug 27, 2026
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Process Development & Improvement Scientist

Medgene Labs

Brookings, SD, USA Full-time On-site

Medgene Labs' Process Development team advances livestock immunology by creating recombinant protein vaccines. The Scientist executes process development and improvement studies, runs small‑scale bioreactors, maintains aseptic techniques, and documents work to meet CVB regulations.

Last seen Sep 3, 2026
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Medical Laboratory Scientist

Avera Health

Sioux Falls, SD, United States of America Full-time On-site $29 - $44 / hour

Medical Laboratory Scientist

Last seen Sep 3, 2026
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Clinical Operations Scientist

Aurion Biotech Inc.

SD Full-time Remote $96,000 - $120,000 / year

Aurion Biotech is a clinical-stage biotechnology company dedicated to restoring vision through regenerative therapies, with its lead allogeneic cell therapy for corneal edema PMDA-approved in Japan and in Phase 3 trials in the US. The Clinical Operations Scientist serves as a scientific resource for assigned ophthalmology studies, contributing to protocol development, data review, regulatory interactions, and dissemination of scientific findings while supporting clinical trial execution. The rol

Last seen Sep 3, 2026
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R&D Research- Associate Scientist

Medgene Labs

Brookings,SD,USA Full-time On-site

R&D team at Medgene Labs develops immunological products to protect livestock. The Associate Scientist conducts and designs immunological assays, processes clinical samples, and performs data analysis to support vaccine research across multiple species.

Last seen Sep 3, 2026
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Medical Laboratory Scientist - Vermillion - PT

Sanford Health

Vermillion,SD,United States Part-time On-site $24 - $44 / hour

Clinical Laboratory team at Sanford Health provides essential diagnostic testing for patients in Vermillion. The Medical Laboratory Scientist performs pre‑analytical, analytical, and post‑analytical testing, operates manual and automated equipment, and ensures safety and quality compliance.

Last seen Sep 3, 2026
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Global Pharmacovigilance Senior Scientist

Amgen

Sioux Falls,South Dakota,USA Full-time Remote $140,799 - $190,493 / year

Global Pharmacovigilance team at Amgen safeguards patient safety across therapeutic areas. The Senior Scientist leads safety assessment activities, authoring aggregate reports, risk management plans, and regulatory submissions while guiding cross‑functional teams and affiliates.

Last seen Aug 26, 2026
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Medical Laboratory Technician or Scientist

Regional Health

Spearfish, SD, USA Full-time

10th St Laboratory at Monument Health provides essential diagnostic services to the Spearfish community. The team performs routine and complex laboratory tests, ensures specimen integrity, and supports quality assurance and equipment calibration.

Last seen Sep 3, 2026
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Medical Laboratory Technician/Scientist

Avera Health

Mitchell, SD, United States Full-time On-site $24 - $44 / hour

Medical Laboratory team at Avera Queen of Peace Hospital performs a wide range of clinical tests and ensures quality control of lab operations. The technician operates instrumentation, manages inventory, calibrates equipment, and communicates results to providers.

Last seen Aug 21, 2026
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Medical Laboratory Technician / Scientist

Regional Health

Sturgis,SD,USA Full-time On-site $24 - $40 / hour

STH Laboratory at Monument Health provides essential diagnostic testing to support patient care. The role performs specimen collection, prepares samples, conducts routine and complex lab tests, ensures quality and calibration of equipment, and reports results to physicians while supervising new staff.

Last seen Sep 3, 2026
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Medical Laboratory Scientist or Tech

Avera Health

Britton, SD, United States Full-time On-site

Marshall County Healthcare Center seeks a Medical Laboratory Scientist or Technician to support patient care through high‑volume laboratory testing. The role collects, processes, and analyzes blood samples, ensures quality assurance, and troubleshoots instrument and methodological issues.

Last seen Sep 3, 2026
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Satellite-Derived Bathymetry Scientist

KBR

Sioux Falls, South Dakota, United States Full-time Hybrid

Science and Space division TSSC team at KBR supports USGS EROS Center Integrated Science and Applications Branch, advancing satellite-derived bathymetry for coastal and riverine mapping. The Scientist conducts imagery acquisition, validates datasets, applies AI/ML to enhance SDB algorithms, and collaborates with remote sensing experts.

Last seen Aug 21, 2026
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Medical Laboratory Scientist, Float - FT

Sanford Health

Sioux Falls,SD,United States of America Full-time $30 - $44 / hour

Sanford Health’s Laboratory Services team delivers high‑quality diagnostics across Sioux Falls and surrounding sites. As a float MLS, you’ll perform pre‑analytical, analytical, and post‑analytical testing, troubleshoot equipment, and train new staff while rotating through Family Medicine, Women’s, Pediatrics, Oncology and Acute Care labs.

Last seen Sep 3, 2026
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Medical Lab Scientist (MLS) | Temporary

Avera Health

Sioux Falls, SD, United States of America Full-time $29 - $44 / hour

Temporary Medical Lab Scientist supporting Avera’s EPIC transition at McKennan Hospital. Responsibilities include validation, workflow testing, SOP development, staff training, go‑live support, quality monitoring, and continuous improvement.

Last seen Sep 3, 2026
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Research & Development (R&D) / Product Development Scientist

FARMERS UNION INDUSTRIES LLC

Mitchell,SD,USA Full-time On-site

Performance Pet Products team develops and commercializes canned wet pet foods, leading formulation and reformulation efforts to meet quality, cost and regulatory standards. The scientist designs samples, evaluates ingredient alternatives, supports shelf‑life studies and works with quality, sales and operations to improve product consistency and manufacturing efficiency.

Last seen Sep 3, 2026
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Data Scientist Jobs in South Dakota: FAQ

How many Data Scientist jobs in South Dakota are open right now?

58 Data Scientist jobs in South Dakota are live on NextGig, all seen active within the last 45 days. The list refreshes daily as new roles are posted and filled ones drop off.

Which companies are hiring for Data Scientist jobs in South Dakota?

Employers with current openings include Sterling Computers, Humana, Highmark Health and Allegheny Health Network, CrowdStrike, CVS Health, Avera Health, and others. Every listing links straight to the employer's application page.

What do Data Scientist jobs in South Dakota pay?

13 of the 20 newest listings disclose pay, for example $156,500 - $215,300 / year at Humana, $102,700 - $164,600 / year at Highmark Health and Allegheny Health Network, $140,000 - $215,000 / year at CrowdStrike. Open a listing for the full compensation details.

Are any of these roles remote?

Of the 20 newest listings on this page, 5 are remote and 1 is hybrid. The work model is shown on each job card.