Full-time Jobs in South San Francisco, California, United States

We are seeking an accomplished and highly motivated Principal Scientist to provide strategic and scientific biomarker leadership across programs within the Cardiovascular & Metabolic and Infectious Diseases/Vaccines portfolios. This role will lead the design, execution, analysis, and communication of translational and clinical biomarker strategies across programs spanning early through late clinical development.

The Senior Specialist, Publication Operations role supports AbbVie's Global Scientific Publications (GSP) Team in South San Francisco, California. Day-to-day work includes operational support for scientific congress activities (poster shipping, printing, QR code creation, calendar management), end-to-end vendor management (billing, P.O. maintenance, oversight), invoice analysis, and budgetary reconciliation.

The Therapeutic Area Analytics & Insights Director - Foundational Products Access Lead sits within Genentech's Data, Digital & Analytics (DDA) team, serving Commercial, Medical, and Government Affairs (CMG) partners. Day-to-day, the role synthesizes access, market research, forecasting, and competitive intelligence insights to advise senior leaders on in-line, pipeline, and business development decisions across the Oncology, Immunology, Lytics, and Flu therapy areas, while coaching 1–2 contribut

Regulatory Affairs at Sentibio leads the development and execution of CMC regulatory strategies for complex cell therapy products. The Senior Director defines global CMC regulatory goals, oversees IND, BLA, CTA, and MAA submissions, and coordinates cross‑functional teams to ensure compliance and timely delivery.

Calico, an Alphabet‑backed life‑science company, seeks a Principal Scientist to integrate computational design with experimental antibody development. The role bridges the wet‑lab team and machine‑learning engineers, translating in‑silico predictions into actionable experiments and feeding results back into predictive models.

The Associate Principal Scientist, Discovery Oncology, Reverse Translation role joins a bicoastal Discovery Oncology, Reverse Translation Team in South San Francisco, California. Day-to-day work involves designing, executing, analyzing, and presenting laboratory studies that leverage clinical insights, in vitro systems, and in vivo oncology models to identify novel therapeutic targets and elucidate mechanisms of tumor biology, disease progression, and therapeutic response.

Platforms team at Aechelon Technology builds automated Windows-based storage platforms for real-time graphics simulators. The engineer designs, scripts and scales Storage Spaces Direct deployments, creates CI/CD pipelines, and supports high‑availability and security integration.

In this vital role you will contribute to the discovery and advancement of innovative therapies for rare diseases as a core member of multidisciplinary, disease-focused research teams. You will apply experimental and data-driven approaches to investigate disease mechanisms, evaluate novel therapeutic targets, and generate insights that inform scientific and portfolio decisions.

Process Sciences group within Process and Product Development at Allogene Therapeutics focuses on advancing cell therapy manufacturing. The Principal Scientist leads design and execution of cell starting material characterization, develops isolation technologies, and drives process control strategies for GMP production.

A transit driver position with MV Transportation in South San Francisco, CA. The role requires a Class B CDL with air brake and passenger endorsements, a minimum of five years of safe driving history, and the ability to work a varied schedule including evenings, weekends, and holidays. Drivers will safely operate fixed-route commercial vehicles, assist riders, secure mobility devices, and provide friendly customer service while adhering to all safety policies and traffic regulations.

MV Transportation Maintenance Team ensures reliable vehicle operation for transit services. The mechanic performs preventative maintenance, diagnoses issues, and repairs steering, suspension, brakes, engines, transmissions, electrical systems, wheelchair lifts, and HVAC.

Home Health Team at 21st Century Home Health Services provides compassionate in‑home care to patients across the Bay Area. The Certified Home Health Aide delivers personal care, assists with daily living activities, and reports patient status to the RN Case Manager.

Allied Universal seeks an Armed Security Officer - Armed Patrol to safeguard a technology-focused site in South San Francisco, CA. You will conduct armed patrols, maintain a visible deterrent presence, monitor access control, and deliver customer service to employees, visitors, and contractors. The role also involves responding to incidents and alarms, coordinating with site contacts and emergency responders, and completing accurate activity logs and incident reports.

Amgen seeks a Senior Director – BioIntelligence to lead AI & Data for Engineered Biologics. The role drives AI‑driven predictive modeling for biologics discovery, guiding a multidisciplinary team of machine learning scientists and computational biologists.

K1 Speed South San Francisco location, On-site. Leads the center to meet K1 standards, overseeing staffing, cash handling, facility compliance, marketing and daily operations.

AbbVie Biotherapeutics Inc.'s Analytical Research & Development team in South San Francisco, CA seeks a Senior Scientist 1, Bioassay Development to develop and optimize complex bioassays and target-binding potency assays critical for biotherapeutic development. Day-to-day work includes qualifying and validating potency methods, collaborating cross-functionally with Discovery, CMC, QC, and QA teams, authoring technical documents for regulatory submissions, and troubleshooting assay performance.

Our expanding In Vivo Pharmacology group in South San Francisco, CA has an opening for a motivated tumor biologist who is dedicated to the discovery and development of innovative therapeutics, both small molecule and biologics, with a focus on immuno-oncology. The Scientist I will perform tumor efficacy and PK/PD studies and provide pharmacology support to innovative cancer drug development.

Data Science, Automation & Machine Learning team at Aechelon Technology creates high‑fidelity 3D simulation content for pilot training. The Data Annotator produces precise vector annotations and segmentation masks for computer‑vision models, validates outputs, and documents workflows while collaborating with Advanced Model Development and Applied Real‑Time Vision groups.

The Senior Medical Director, Product Development, Neurology at Roche’s Clinical Development organization leads the development and execution of late-stage (Phase II–III) clinical strategies and plans for assigned neurology molecules/indications. Day-to-day, the role independently leads multiple projects, drives cross-functional integration and alignment, represents Clinical Development to internal groups, leads health authority interactions and regulatory filings, and mentors new CST members.