Jobs in South San Francisco, California, United States

10,000 jobs available

Find 10,000 local jobs in South San Francisco, California, United States. Connect with employers hiring in South San Francisco and take the next step in your career today.

Showing 20 of 10,000 jobs

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Compensation Manager

Zipline

South San Francisco,California,USA Full-time On-site USD150,000 - USD230,000 / year

People Operations at Zipline designs and operates the world’s autonomous logistics system, delivering critical supplies globally. The Compensation Manager leads the development of compensation philosophy, frameworks, and governance, partnering with senior leaders, recruiting, finance, and HR to shape pay strategies and tools.

Last seen Jul 20, 2026
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Labs FSP Associate Scientist - Synthetic Chemistry

Thermo Fisher Scientific

South San Francisco,California,USA Full-time On-site USD30 - USD34 / hour

Analytical Services team, Department of Synthetic Molecule Process Chemistry at Thermo Fisher Scientific. Conducts process chemistry experiments, develops crystallization methods, and scales syntheses to kilogram scale while documenting results in electronic lab notebooks.

Last seen Jul 20, 2026
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Senior Product Designer

Notable

San Mateo,California,USA Full-time Hybrid USD175,280 - USD219,100 / year

Product Design Team at Notable builds AI-powered healthcare workflow tools to improve patient and staff experiences. The Senior Product Designer shapes complex enterprise SaaS interfaces, creates design systems, and partners with product and engineering to iterate and ship solutions.

Last seen Jul 20, 2026
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Global Supply Management Intern (Fall 2026)

Zipline

South San Francisco,California,USA Internship On-site

Global Supply Management Intern at Zipline, part of the Global Supply Chain Team that ensures reliable, sustainable sourcing for the world’s autonomous logistics network. The role supports sourcing, analytics, and day‑to‑day execution by tracking supplier performance, preparing dashboards, gathering quotes, and collaborating with engineering, finance and operations.

Last seen Jul 20, 2026
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Java 11 changes limited with CWS Associate - Product - Engineer

Oneco 1

San Mateo,California,USA Full-time On-site
Last seen Jul 20, 2026
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AI Platform Engineer

Notable

San Mateo,California,USA Full-time Hybrid USD170,000 - USD205,000 / year

Notable AI Platform builds AI-driven automation to improve healthcare workforce productivity. As a Senior AI Platform Engineer you will design, build, and maintain LLM integrations, translate ambiguous problems into technical plans, and own end‑to‑end delivery while ensuring scalability and reliability.

Last seen Jul 20, 2026
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AI Content Intern

Fireworkhq

San Mateo,California,USA Internship Hybrid USD19 - USD25 / hour

Creative Services team at Firework builds AI-driven video commerce experiences. As an AI Content Intern you will partner with R&D, Creative Services, and Product to apply generative AI tools to create and launch content for real brands, documenting workflows and coordinating cross‑functional efforts.

Last seen Jul 20, 2026
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Service Manager

Bridgestone

San Mateo,CA,USA Full-time On-site USD25 - USD37 / hour

Bridgestone Retail Operations (BSRO) seeks a Service Manager to lead a team of automotive technicians in San Mateo, CA. The role schedules work, trains staff, and ensures customer satisfaction while driving sales and maintaining quality standards. On-site work at the San Mateo store with a supportive onboarding and ongoing training program.

Last seen Jul 20, 2026
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Senior Scientist, Molecular Discovery

Merck

South San Francisco,California,USA Full-time On-site USD131,400 - USD206,800 / year

Protein Sciences department at Merck Discovery Biologics focuses on advancing biologics discovery through biophysics, protein engineering, and computational design. The Senior Scientist designs, executes, and interprets SPR and biosensor assays, collaborates with computational teams to generate AI/ML‑driven datasets, and mentors junior scientists.

Last seen Jul 20, 2026
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Test Equipment Design Engineer, Battery and Power Electronics

Zipline

South San Francisco,California,USA Full-time On-site

Battery & Power Electronics team at Zipline designs and validates power systems for autonomous delivery aircraft. The role develops custom electromechanical test equipment—mechanical frames, hydraulic/pneumatic actuators, instrumentation and automation—to characterize, qualify and manufacture battery and power electronics hardware.

Last seen Jul 20, 2026
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SUPPORT-2634 Testing

Oneco 1

San Mateo,California,USA Full-time On-site
Last seen Jul 20, 2026
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Scientist - In Vivo

Merck

South San Francisco,California,USA Full-time On-site USD108,000 - USD170,100 / year

Cardiometabolic Disease Department at Merck conducts research to discover and develop therapies for metabolic disorders. The Associate Scientist designs, executes, and interprets in vivo, ex vivo and in vitro studies, establishes assays and model systems, and presents findings to cross‑functional teams.

Last seen Jul 20, 2026
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Supply Chain Business Operations Manager, AI Strategy

Zipline

South San Francisco,California,USA Full-time On-site

Supply Chain Business Operations at Zipline focuses on building AI-driven workflows to ensure reliable aircraft parts supply and improve delivery performance. The manager owns AI strategy, translating operational pain points into production‑grade tools, prototypes, and automated web apps that boost on‑time delivery, quality, and cost metrics.

Last seen Jul 20, 2026
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Senior Producer

Zipline

South San Francisco,California,USA Full-time On-site

Marketing Production team at Zipline builds and scales the creative and marketing ecosystem that delivers high‑quality, on‑brand experiences across print, OOH, retail, events, packaging, direct mail and digital. The Senior Producer leads end‑to‑end production, manages vendors and budgets, and creates scalable workflows and operating rhythms to keep projects on time and on budget.

Last seen Jul 20, 2026
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Senior Regulatory Affairs Director - Oncology Cell & Gene Therapy

AstraZeneca

South San Francisco,California,USA Full-time Hybrid USD218,058 - USD327,088 / year

Regulatory Affairs at AstraZeneca, Oncology Cell & Gene Therapy team drives global regulatory strategy for high‑complexity CGT products targeting multiple myeloma. The Senior Director leads the Global Regulatory Strategy Team, shapes BLA submissions, manages health authority interactions, mentors cross‑functional partners, and develops novel regulatory tools.

Last seen Jul 14, 2026
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Flight Test Operator

Zipline

South San Francisco,California,USA Full-time On-site

Flight Test Operations at Zipline focuses on validating autonomous aircraft from prototype to production. The role executes daily flight test campaigns, acts as Remote Pilot in Command, and collaborates with engineering, safety, and manufacturing to ensure airworthiness and reliable delivery.

Last seen Jul 20, 2026
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Cardiac Sonographer I

Sutter Health

San Mateo,CA,USA Contract On-site

MPHS-Mills-Peninsula Medical Center performs diagnostic cardiac sonography to assess cardiac structures and hemodynamics. The Cardiac Sonographer I conducts standard echocardiography, transesophageal studies, intra‑operative TEE, structural heart procedures in the cath lab, and complex congenital pediatric exams.

Last seen Jul 20, 2026
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AI/ML Lead Engineer

QS Investors

San Mateo,California,USA Full-time Hybrid USD180,000 - USD212,000 / year

AI platform team at Franklin Templeton builds multi‑agent AI solutions that empower financial advisors with data‑driven insights. The Lead Engineer designs and implements production‑grade multi‑agent systems, develops distributed services, and establishes evaluation frameworks to ensure accuracy, compliance, and reliability.

Last seen Jul 20, 2026
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Talent Attraction Program Manager

Zipline

South San Francisco,California,USA Full-time

Talent Attraction team at Zipline, the world’s largest drone delivery service, builds employer brand and recruiting events to fuel rapid growth. The role designs and executes conference, hackathon and open‑house strategies, partners with marketing and exec stakeholders, and measures impact through hire conversion and pipeline quality.

Last seen Jul 14, 2026
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Mechanical Design Engineer - Droid SMI

Zipline

South San Francisco,California,USA Full-time On-site

Hardware Team at Zipline builds the delivery droid, a consumer‑visible container that must be beautiful, cheap, quiet, weatherproof and reliable for tens of thousands of flight cycles. The Mechanical Design Engineer owns droid subsystems end‑to‑end, from architecture and CAD (Siemens NX) through prototyping, validation, DFM, tooling and production ramp, partnering with industrial designers and cross‑functional engineers.

Last seen Jul 20, 2026
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Jobs in South San Francisco: FAQ

How many jobs in South San Francisco are open right now?

10,000 jobs in South San Francisco are live on NextGig, all seen active within the last 45 days. The list refreshes daily as new roles are posted and filled ones drop off.

Which companies are hiring for jobs in South San Francisco?

Employers with current openings include Zipline, Thermo Fisher Scientific, Notable, Oneco 1, Fireworkhq, Bridgestone, and others. Every listing links straight to the employer's application page.

What do jobs in South San Francisco pay?

10 of the 20 newest listings disclose pay, for example USD150,000 - USD230,000 / year at Zipline, USD30 - USD34 / hour at Thermo Fisher Scientific, USD175,280 - USD219,100 / year at Notable. Open a listing for the full compensation details.

Are any of these roles remote?

Of the 20 newest listings on this page, 5 are hybrid. The work model is shown on each job card.