Licensed Practical Nurse Jobs in South Carolina, United States

1,000 jobs available

Find Licensed Practical Nurse opportunities in South Carolina, United States. Browse 1,000 open positions from top employers in the area.

Showing 20 of 1,000 jobs

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LPN - FT Night Shift

Summit Behavioral Healthcare

Cameron, South Carolina, United States of America Full-time On-site

Licensed Practical Nurse (LPN) for Night Shift at Waypoint Recovery Center in Cameron, SC. Full-time 12‑hour shifts 7 pm–7 am, three per week. Works under RN supervision, provides direct nursing care, medication administration, vital signs, ECG, phlebotomy, glucose monitoring, and emergency coverage.

Last seen Jul 12, 2026
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LPN, Mullins Nursing Center, PRN (8hr and 12hr shifts available)

Medical University of South Carolina (MUSC)

Mullins, South Carolina, United States of America Part-time On-site

Licensed Practical Nurse (LPN) position at Mullins Nursing Center, part‑time PRN. The role offers 8‑hour and 12‑hour shifts to accommodate student schedules and extra coverage needs. LPNs provide patient‑and-family‑centered care, acting as partners and advisers, supporting patients in managing health care while respecting culture, values, and treatment preferences.

Last seen Jul 12, 2026
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LPN Licensed Practical Nurse

NHC and Affiliates

Sumter, SC, United States Full-time On-site

NHC HealthCare Sumter seeks a Licensed Practical Nurse to join our dedicated team. The role focuses on maintaining clinical competency, applying nursing knowledge, and delivering compassionate care to geriatric patients.

Last seen Jul 13, 2026
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LPN

Medical University of South Carolina (MUSC)

Orangeburg,SC,US Full-time

MUSC Women's Health - Orangeburg provides comprehensive women's health services. The LPN delivers direct patient care under physician direction, documents medical records, and ensures patient comfort and privacy.

Last seen Jul 12, 2026
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LPN-Hollings of Orangeburg

Medical University of South Carolina (MUSC)

Orangeburg, South Carolina, United States Full-time On-site

Licensed Practical Nurse to provide patient and family centered care at Hollings Cancer Center of Orangeburg. Responsibilities include assisting medical staff with examinations, documenting vital signs, managing patient communications, and maintaining clinical records.

Last seen Jul 12, 2026
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LPN Charge Nurse - FT - Night

Ansley Park Health & Rehab

Richland,GA,United States of America Full-time On-site USD26 - USD29 / hour

Four County Health & Rehab’s Nursing Team delivers compassionate, high‑quality care to residents in Richland, GA. As a Charge Nurse, you will supervise nursing assistants, coordinate patient care plans, manage medication administration, and maintain compliance with federal and state regulations. The role is a full‑time night shift, onsite at the Richland facility, with opportunities for shift differentials and management add‑on pay.

Last seen Jul 12, 2026
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LPN Charge Nurse - Full Time

Vitality Living

Columbia,SC,USA Full-time On-site

Vitality Living’s LPN Charge Nurse leads a compassionate Wellness team at the Columbia, SC community, ensuring residents receive personalized care and medication management. The role coordinates with physicians, manages specimen transport, and updates service plans to reflect resident preferences.

Last seen Jul 12, 2026
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LPN II - Med/Tele (5H)- Columbia DT

Medical University of South Carolina (MUSC)

Columbia,SC,USA Full-time On-site

LPN II on the Med/Tele team at MUHA provides direct patient care in a 36‑hour week of 3 twelve‑hour shifts, including some weekend call. The role involves nursing care, data collection, and care plan formulation under RN supervision.

Last seen Jul 12, 2026
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LPN Pediatric Home Health Nurse

Angels of Care

Columbia,SC,USA Full-time On-site USD28 - USD33 / hour

Angels of Care Pediatric Home Health is a dedicated team focused on delivering high‑quality, one‑on‑one medical care to infants, children, and adolescents in their homes. The LPN role involves daily patient assessments, medication administration, care coordination, and family education to support positive outcomes.

Last seen Jun 25, 2026
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LPN / RN Pediatric Home Health Nurse

Angels of Care

Columbia,SC,USA Full-time|part-time On-site USD26 - USD31 / hour

Angels of Care Pediatric Home Health provides one‑on‑one medical care for infants, children, and adolescents in their homes. The nurse conducts assessments, administers medications, coordinates care, and educates families to improve outcomes.

Last seen Jun 4, 2026
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LPN / RN Pediatric Home Health Nurse

Angels of Care

Camden,South Carolina,USA Full-time On-site

Angels of Care Pediatric Home Health provides one‑on‑one, in‑home care for medically fragile children and young adults, delivering high‑quality, individualized nursing in a compassionate setting. The nurse will perform skilled assessments, administer medications and therapies, coordinate with families and providers, and educate caregivers to ensure optimal outcomes.

Last seen Jul 12, 2026
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LPN II- Complex Intervention Unit

Medical University of South Carolina (MUSC)

University Hospital, South Carolina, United States of America Full-time On-site

Under the direction of a registered nurse, the LPN is responsible for nursing care behaviors within their span of control, accountable to the Charge Nurse, and participates in the care of a defined patient population. The LPN assists with data collection, formulation of care plans, and evaluation of outcomes.

Last seen Jul 11, 2026
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LPN/RN CNA Instructor

Medical University of South Carolina (MUSC)

Columbia, South Carolina, United States of America Full-time On-site

MUSC Health seeks licensed LPN or RN to serve as Nurse Educator in Workforce Development team, teaching DHHS-approved CNA Apprenticeship Program. Responsibilities include delivering classroom, simulation lab, and clinical instruction, preparing students for Nurse Aide Competency Exam, coordinating clinical placements, ensuring compliance, recruiting, retention, and community engagement.

Last seen Jul 12, 2026
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LPN- Corrections Nurse- LPN-NIGHTS

ATC Columbia

Columbia,SC,US Full-time On-site USD30 - USD30 / hour

ATC Columbia Corrections Nursing team provides healthcare services to incarcerated individuals, ensuring safe and compassionate care within correctional facilities. The LPN delivers direct patient care, administers medications, performs wound care, supports rehabilitation activities, and coordinates with supervising nurses and medical staff during night shifts.

Last seen Jul 12, 2026
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LPN - Nurse Supervisor, 2nd Shift

NHC and Affiliates

Columbia, South Carolina, United States Full-time On-site

We are seeking a dedicated LPN Nurse Supervisor for our 2nd shift at The Palmettos of Parklane. In this role you will lead a nursing team, oversee resident care, administer medications, and ensure compliance with South Carolina ALF regulations.

Last seen Jun 17, 2026
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LPN Licensed Practical Nurse

NHC and Affiliates

Columbia, South Carolina, United States Full-time On-site

Licensed Practical Nurse (LPN) position at NHC HealthCare Parklane in Columbia, SC. The role focuses on delivering compassionate, patient-centered care within a family‑oriented environment. Responsibilities include maintaining clinical competency, applying the nursing process for assessment, planning, and implementation, prioritizing patient needs, and integrating state and federal regulations.

Last seen Jul 13, 2026
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LPN Charge Nurse

Lutheran Hospice

Columbia, South Carolina, United States Full-time On-site

Provide nursing care following physician orders and established standards, manage resident mood changes, assist with lifting and turning residents, and respond promptly to emergencies.

Last seen Jul 13, 2026
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LPN Charge Nurse

Lutheran Hospice

Columbia/White Rock, South Carolina, United States Full-time On-site

Provide nursing care per physician orders and facility standards, supervise staff, handle emergencies, and assist with resident lifting and turning.

Last seen Jul 13, 2026
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LPN Weekend Baylor

Lutheran Hospice

Columbia, South Carolina, United States Full-time On-site

Provides compassionate nursing care to hospice residents, following physician orders and established protocols. Manages daily health needs, monitors vital signs, and administers medications.

Last seen Jul 13, 2026
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LPN Weekend Baylor

Lutheran Hospice

Columbia/White Rock, South Carolina, United States Full-time On-site

Provide comprehensive nursing care following physician orders and established standards. Supervise nursing staff on the unit, ensuring quality and compliance.

Last seen Jul 13, 2026
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Licensed Practical Nurse Jobs in South Carolina: FAQ

How many Licensed Practical Nurse jobs in South Carolina are open right now?

1,000 Licensed Practical Nurse jobs in South Carolina are live on NextGig, all seen active within the last 45 days. The list refreshes daily as new roles are posted and filled ones drop off.

Which companies are hiring for Licensed Practical Nurse jobs in South Carolina?

Employers with current openings include Summit Behavioral Healthcare, Medical University of South Carolina (MUSC), NHC and Affiliates, Ansley Park Health & Rehab, Vitality Living, Angels of Care, and others. Every listing links straight to the employer's application page.

What do Licensed Practical Nurse jobs in South Carolina pay?

4 of the 20 newest listings disclose pay, for example USD26 - USD29 / hour at Ansley Park Health & Rehab, USD28 - USD33 / hour at Angels of Care, USD26 - USD31 / hour at Angels of Care. Open a listing for the full compensation details.