Licensed Practical Nurse Jobs in South Dakota, United States

237 jobs available

Find Licensed Practical Nurse opportunities in South Dakota, United States. Browse 237 open positions from top employers in the area.

Showing 20 of 237 jobs

LPN | Medical

Regional Health

Rapid City, South Dakota, United States Full-time On-site $26 - $30 / hour

Licensed Practical Nurse (LPN) provides direct and indirect patient care in inpatient and ambulatory dialysis units under RN or physician supervision. Responsibilities include assessment, medication administration, nursing procedures, care planning, patient education, documentation, and mentoring.

Last seen Oct 11, 2026
View details Apply

RN/LPN/CMA

Community HealthCare Association of the Dakotas

Woonsocket, South Dakota, United States Full-time On-site

Horizon Health in Woonsocket, SD seeks an RN, LPN, or CMA to deliver patient-centered care within its outpatient clinic. The role splits duties between front-office coordination and direct nursing tasks, including rooming patients, administering treatments, and managing schedules.

Last seen Oct 11, 2026
View details Apply

RN/ LPN or CMA

Community HealthCare Association of the Dakotas

Yankton, South Dakota, United States Full-time On-site

Horizon Health in Yankton, SD provides outpatient nursing care within its community clinic. The role coordinates patient visits, records vitals and history in the EHR, educates patients, and performs nursing tasks such as injections, vaccinations, labs and x‑rays.

Last seen Oct 11, 2026
View details Apply

RN/LPN/CMA

Community HealthCare Association of the Dakotas

Wessington Springs, South Dakota, United States Full-time On-site

Horizon Health in Wessington Springs, SD seeks an RN, LPN, or CMA to deliver patient-centered care in its outpatient clinic. The role involves coordinating patient visits, performing clinical skills like injections and labs, and providing health education within a collaborative team environment.

Last seen Oct 11, 2026
View details Apply

LPN | Gastroenterology

Regional Health

Rapid City, South Dakota, United States Full-time On-site $25 - $29 / hour

Licensed Practical Nurse (LPN) in Rapid City ambulatory gastroenterology clinic. Provides direct patient care under RN/physician supervision, performs nursing procedures, administers medications, documents vital signs, and manages patient education.

Last seen Oct 11, 2026
View details Apply

LPN | Nephrology

Regional Health

Rapid City, South Dakota, United States Full-time On-site $25 - $29 / hour

The Licensed Practical Nurse (LPN) in Nephrology at Monument Health Rapid City Clinic provides direct and indirect patient care in an ambulatory setting. Working under the supervision of a physician or RN, the LPN delivers nursing care in accordance with Monument Health policies, South Dakota Nurse Practice Act, and applicable regulations.

Last seen Oct 11, 2026
View details Apply

LPN | Medical

Regional Health

Rapid City, South Dakota, United States Full-time $26 - $30 / hour

LPN on the Rapid City Medical team at Monument Health delivers direct and indirect patient care in inpatient and ambulatory dialysis units, collaborating with RNs and physicians to assess, treat, and document patient needs. The role involves medication administration, nursing procedures, patient education, and participation in quality improvement and onboarding.

Last seen Oct 11, 2026
View details Apply

LPN | Gastroenterology

Regional Health

Rapid City, South Dakota, United States Full-time On-site $25 - $29 / hour

LPN on the Gastroenterology team at Monument Health Rapid City Clinic provides direct patient care in an ambulatory setting, collaborating with physicians and RNs to deliver quality nursing services. The role involves preparing exam areas, documenting vital signs, administering medications, and supporting patient education while adhering to South Dakota Nurse Practice Act standards.

Last seen Oct 11, 2026
View details Apply

LPN | Medical

Regional Health

Rapid City, South Dakota, United States Full-time On-site $26 - $30 / hour

The Licensed Practical Nurse (LPN) will provide direct and indirect patient care in inpatient and ambulatory dialysis units at Monument Health Rapid City Hospital. Working under the supervision of physicians or registered nurses, the LPN will conduct focused assessments, administer medications, perform nursing procedures, and document care in accordance with state regulations and hospital policies.

Last seen Oct 11, 2026
View details Apply

Apprenticeship ~ LPN

Huron Regional Medical Center

Huron, South Dakota, United States Full-time On-site

Huron Regional Medical Center Apprenticeship LPN program rotates the apprentice through 4-6 nursing areas under RN supervision, allowing 2-4 weeks of hands‑on patient care, communication, and care coordination. The role supports direct nursing care for individual clients with defined diagnoses and organizes nursing tasks during each work period.

Last seen Oct 11, 2026
View details Apply

LPN | Cardiology Clinic

Regional Health

Rapid City, South Dakota, United States Full-time On-site $25 - $29 / hour

Licensed Practical Nurse (LPN) in the Cardiology Clinic at Monument Health Rapid City Hospital provides direct and indirect patient care in an ambulatory setting. The LPN works under physician or RN supervision, performing nursing procedures, medication administration, vital sign collection, and documentation per clinic standards.

Last seen Oct 11, 2026
View details Apply

RN/LPN/CMA

Community HealthCare Association of the Dakotas

Elk Point, South Dakota, United States Full-time On-site

Horizon Health in Elk Point, SD seeks an RN, LPN, or CMA to deliver patient-centered nursing care within its outpatient clinic. The role involves coordinating patient visits, performing clinical skills like injections and labs, and providing health education.

Last seen Oct 11, 2026
View details Apply

LPN - LTC

Winner Regional Healthcare Center

Winner, South Dakota, United States Full-time On-site $24 - $32 / hour

Licensed Practical Nurses in long‑term care provide comprehensive, patient‑centered nursing services in a skilled‑living environment. They apply the nursing process to assess, plan, implement, and evaluate care for residents, ensuring compliance with state regulations and facility policies.

Last seen Oct 11, 2026
View details Apply

LPN | Pain Management

Regional Health

Rapid City, South Dakota, United States Full-time On-site $25 - $29 / hour

MHOSH Pain Management team at Monument Health provides ambulatory pain care. The LPN delivers direct and indirect patient care, prepares exam rooms, records vitals, administers meds, and supports RN/physician oversight.

Last seen Oct 11, 2026
View details Apply

LPN | Behavioral Health

Regional Health

Rapid City, South Dakota, United States Full-time On-site $26 - $29 / hour

The Licensed Practical Nurse (LPN) in Behavioral Health at Monument Health Rapid City Hospital provides direct and indirect patient care in inpatient and ambulatory dialysis units. Working under the supervision of a physician or RN, the LPN administers medications, performs nursing procedures, and implements clinical interventions to improve patient outcomes.

Last seen Oct 11, 2026
View details Apply

LPN or RN, Full Time Nights

Sanford Health

Canistota, South Dakota, United States Full-time On-site

Sanford Health, the largest rural health system in the United States, delivers world‑class care to communities across the heartland. As a Registered Nurse or Licensed Practical Nurse on the night shift, you will provide comprehensive nursing care, assess and coordinate resident treatment, and may serve as charge nurse delegating tasks to support staff.

Last seen Oct 8, 2026
View details Apply

LPN| AESS Temp Staffing | PRN

Avera Health

Sioux Falls, SD Part-time On-site $24 - $33 / hour

Licensed Practical Nurse (LPN) supporting Avera Health across multiple South Dakota and Nebraska sites. Works under RN or advanced practice supervision, coordinating patient care and nursing diagnoses.

Last seen Oct 11, 2026
View details Apply

LPN or Medical Assistant

Regional Health

Box Elder, South Dakota, United States Full-time On-site $20 - $29 / hour

Monument Health Box Elder Clinic (Ambulatory Nursing) provides compassionate primary care in a collaborative team environment. The LPN or Medical Assistant delivers direct and indirect patient care, prepares exam rooms, records vital signs, administers medications, performs EKGs and lab tests, and supports providers with documentation and scheduling.

Last seen Oct 11, 2026
View details Apply

RN/LPN/CMA

Community HealthCare Association of the Dakotas

Fort Thompson, SD Full-time On-site

Horizon Health in Fort Thompson, SD seeks an RN, LPN, or CMA to deliver patient-centered care in its outpatient clinic. The role involves coordinating patient visits, performing clinical skills like injections and labs, and providing health education within a collaborative team environment.

Last seen Oct 11, 2026
View details Apply

LPN | Cardiology Clinic

Regional Health

Rapid City, South Dakota, United States Full-time On-site $25 - $29 / hour

Cardiology Clinic (Monument Health) provides outpatient cardiac care to the Rapid City community. The LPN delivers direct patient care, prepares exam rooms, records vital signs, administers medications, and supports physicians and RNs in treatment plans.

Last seen Oct 11, 2026
View details Apply

Licensed Practical Nurse Jobs in South Dakota: FAQ

How many Licensed Practical Nurse jobs in South Dakota are open right now?

237 Licensed Practical Nurse jobs in South Dakota are live on NextGig, all seen active within the last 45 days. The list refreshes daily as new roles are posted and filled ones drop off.

Which companies are hiring for Licensed Practical Nurse jobs in South Dakota?

Employers with current openings include Regional Health, Community HealthCare Association of the Dakotas, Huron Regional Medical Center, Winner Regional Healthcare Center, Sanford Health, Avera Health. Every listing links straight to the employer's application page.

What do Licensed Practical Nurse jobs in South Dakota pay?

13 of the 20 newest listings disclose pay, for example $26 - $30 / hour at Regional Health, $25 - $29 / hour at Regional Health, $25 - $29 / hour at Regional Health. Open a listing for the full compensation details.