Licensed Practical Nurse Jobs in South Dakota, United States

79 jobs available

Find Licensed Practical Nurse opportunities in South Dakota, United States. Browse 79 open positions from top employers in the area.

Showing 20 of 79 jobs

S

LPN or Medical Assistant - Pierre Clinic - PRN

Sanford Health

Pierre,SD,USA Part-time On-site USD19 - USD30 / hour

Sanford Health, the largest rural health system in the United States, provides patient care at the Pierre Clinic. The LPN/Medical Assistant ensures patient health, comfort, and safety, documents medical histories, administers medications, supports clinical staff, and counsels patients under RN supervision.

Last seen Jul 12, 2026
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A

LPN Admissions - $5k Bonus

Acadia Healthcare

Canton,SD,US Full-time On-site USD24 - USD36 / hour

Keystone Treatment Center - Canton team provides inpatient substance use disorder and mental health care. The LPN delivers patient monitoring, basic nursing care, medication administration, and collaborates with RN and physicians to ensure safety and wellness.

Last seen Jul 12, 2026
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A

LPN Admissions - $5k Bonus

Acadia Healthcare

Canton,SD,US Full-time On-site USD24 - USD36 / hour

Keystone Treatment Center – a nationally recognized inpatient and outpatient facility for substance use and mental health disorders – provides compassionate care to adolescents and adults. The LPN delivers direct patient care, administers medications, monitors health status, and collaborates with the care team to ensure safety and wellness.

Last seen Jul 8, 2026
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S

LPN - Licensed Practical Nurse - FT - Straight Nights

Sanford Health

Miller,SD,United States Full-time On-site USD24 - USD36 / hour

Long Term Care team at Sanford Health provides compassionate nursing care for residents of all ages in a rural setting. The Licensed Practical Nurse delivers direct patient care, administers medications, documents care, and collaborates with interdisciplinary teams during 12‑hour night shifts.

Last seen Jul 12, 2026
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S

LPN - Chamberlain Clinic - Full Time

Sanford Health

Chamberlain, SD, United States of America Full-time On-site USD22 - USD30 / hour

Sanford Health is seeking a Licensed Practical Nurse (LPN) for the Chamberlain Clinic in Chamberlain, SD. The LPN will work a 37‑hour day shift, providing patient care under RN or physician supervision. Responsibilities include ensuring patient safety, documenting medical histories, administering medications, offering technical support, and counseling patients and families on prevention and treatment plans.

Last seen Jul 13, 2026
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F

LPN - 1:1 Pediatric Home Health, WHITE LAKE

Family First Homecare

Chamberlain, SD, United States of America Full-time On-site USD28 - USD34 / hour

Family First Homecare provides exceptional homecare services to children with life-long health conditions. We live by our values of telling the truth, owning the details, and raising the bar, working hard to make your job an experience that you enjoy every day.

Last seen Jul 11, 2026
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W

LPN - Clinic

Winner Regional Healthcare Center

Winner, SD, USA Full-time On-site

Licensed Practical Nurse (LPN) at Winner Regional Healthcare Center provides comprehensive patient care in a clinic setting. Responsibilities include assessing patients, administering medications, performing basic procedures such as phlebotomy, and delivering health education.

Last seen Jul 13, 2026
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S

LPN Long Term Care (LTC)

Sanford Health

Howard,SD,USA Full-time On-site USD26 - USD34 / hour

Licensed Practical Nurse provides nursing care for residents in long‑term care under RN supervision. Performs assessments, medication administration, documentation, and emergency response.

Last seen Jul 12, 2026
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1

LPN

10 Monument Health Rapid City Hospital, Inc.

Western South Dakota, United States Full-time On-site USD25 - USD28 / hour

Licensed Practical Nurse (LPN) position at Monument Health Rapid City Hospital, Inc. Provides direct and indirect patient care in ambulatory settings under RN or physician supervision. Responsibilities include preparing exam areas, patient rooming, vital signs, medication administration, nursing procedures, assessments, documentation, patient education, inbox management, onboarding, and departmental development.

Last seen Jul 12, 2026
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B

LPN Float

Benedictine Health System

Ellendale, ND, USA Contract On-site USD40 - USD40 / hour

Seeking an LPN Float to deliver quality care across multiple Benedictine facilities. The role requires travel within the region, applying Relationship Based Care principles, and working under RN supervision.

Last seen Jun 2, 2026
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B

LPN Float

Benedictine Health System

Ellendale,ND,USA Full-time USD40 - USD40 / hour

LPN Float on the Benedictine Living Community‑Ellendale team, delivering quality, relationship‑based care under RN supervision across multiple Benedictine facilities in the region. The role involves traveling to assigned sites, collecting resident data, and providing hands‑on nursing support while upholding the organization’s core values of Hospitality, Stewardship, Respect, and Justice.

Last seen Jul 12, 2026
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C

RN/LPN-Tiospaye Topa School

Community HealthCare Association of the Dakotas

La Plant,SD,USA Full-time On-site

Horizon Health in Tiospaye Topa School provides outpatient nursing care to the local community. The RN/LPN coordinates patient visits, records vitals, updates EHR, educates patients, and performs injections, vaccinations, labs and x‑rays.

Last seen Jul 12, 2026
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C

RN/ LPN or CMA

Community HealthCare Association of the Dakotas

Eagle Butte,SD,USA Full-time On-site

Horizon Health in Eagle Butte, SD provides outpatient clinic care across Eagle Butte, Isabel, Faith, and Bison. The RN/LPN/CMA role coordinates patient visits, records vitals, updates EHR, educates patients, and performs nursing skills such as injections, vaccinations, labs, and x‑rays.

Last seen Jul 12, 2026
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F

RNs / LPNs - Private Duty Pediatric Homecare (SOUTH DAKOTA)

Family First Homecare

Hoven, SD, USA Full-time

Family First Homecare delivers 1:1 pediatric private duty care across South Dakota, supporting children with life‑long health conditions in their homes. The RN/LPN role provides comprehensive nursing services, including G‑tube, trach, ventilator, seizure monitoring, and infusion care, while maintaining accurate clinical records and collaborating with physicians.

Last seen Jul 12, 2026
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F

RN / LPN: Pediatric Home Health (LEOLA)

Family First Homecare

Leola, South Dakota, United States Full-time On-site

Family First Homecare provides exceptional homecare services to children with life‑long health conditions. This RN/LPN role delivers in‑home nursing care to pediatric patients, including feeding tube care, suctioning, medication management, and documentation.

Last seen Jul 12, 2026
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A

Licensed Practical Nurse (LPN) | Med Surg

Avera Health

Pierre,SD,United States of America Full-time On-site USD27 - USD39 / hour

Avera St Mary's Hospital’s Med Surg team delivers compassionate, patient‑centered care in Pierre, SD. As an LPN, you’ll conduct focused assessments, collaborate on care plans, implement interventions, and advocate for patients while working rotating shifts across days, evenings, nights, weekends, and holidays. The role supports a multidisciplinary team, ensuring safe, effective nursing care and continuous improvement in a supportive, on‑site environment.

Last seen Jul 12, 2026
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A

Licensed Practical Nurse (LPN) | Med Surg

Avera Health

Pierre,SD,United States Full-time On-site USD27 - USD39 / hour

Avera St Mary's Hospital provides compassionate, multidisciplinary care to move health forward. The LPN delivers patient assessments, implements and evaluates nursing interventions, and collaborates with the health team to ensure safe, effective care.

Last seen Jul 12, 2026
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A

Licensed Practical Nurse (LPN) | Long Term Care

Avera Health

Pierre, SD, United States Full-time On-site USD27 - USD39 / year

Licensed Practical Nurse (LPN) in long‑term care at Avera Mary House. Provides nursing care, assessments, medication administration via Pyxis, participates in care planning, uses SBAR, documents, guides staff, and collaborates with physicians and team.

Last seen Jul 12, 2026
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A

Licensed Practical Nurse (LPN) | Same Day Surgery

Avera Health

Pierre, SD Full-time On-site USD27 - USD39 / hour

Licensed Practical Nurse (LPN) | Same Day Surgery

Last seen Jul 12, 2026
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A

Licensed Practical Nurse (LPN) | Long Term Care

Avera Health

Pierre, SD Full-time On-site USD26 - USD38 / hour

Licensed Practical Nurse (LPN) needed for long-term care facility in Pierre, SD. Provide nursing care, assessments, medication administration, care planning, documentation, and communication with RN and physicians. Must hold active LPN license, work night shift, and be able to perform duties with visual acuity and hearing.

Last seen Jul 12, 2026
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Licensed Practical Nurse Jobs in South Dakota: FAQ

How many Licensed Practical Nurse jobs in South Dakota are open right now?

79 Licensed Practical Nurse jobs in South Dakota are live on NextGig, all seen active within the last 45 days. The list refreshes daily as new roles are posted and filled ones drop off.

Which companies are hiring for Licensed Practical Nurse jobs in South Dakota?

Employers with current openings include Sanford Health, Acadia Healthcare, Family First Homecare, Winner Regional Healthcare Center, 10 Monument Health Rapid City Hospital, Inc., Benedictine Health System, and others. Every listing links straight to the employer's application page.

What do Licensed Practical Nurse jobs in South Dakota pay?

15 of the 20 newest listings disclose pay, for example USD19 - USD30 / hour at Sanford Health, USD24 - USD36 / hour at Acadia Healthcare, USD24 - USD36 / hour at Acadia Healthcare. Open a listing for the full compensation details.