Licensed Practical Nurse Jobs in South Dakota, United States

201 jobs available

Find Licensed Practical Nurse opportunities in South Dakota, United States. Browse 201 open positions from top employers in the area.

Showing 20 of 201 jobs

LPN | Nephrology

Regional Health

Rapid City, SD, USA Full-time On-site $25 - $29 / hour

The Licensed Practical Nurse (LPN) in Nephrology at Monument Health Rapid City Clinic provides direct and indirect patient care in an ambulatory setting. Working under the supervision of a physician or RN, the LPN delivers nursing care in accordance with Monument Health policies, South Dakota Nurse Practice Act, and applicable regulations.

Last seen Aug 26, 2026
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LPN | Gastroenterology

Regional Health

Rapid City, SD, USA Full-time On-site $25 - $29 / hour

Licensed Practical Nurse (LPN) in Rapid City ambulatory gastroenterology clinic. Provides direct patient care under RN/physician supervision, performs nursing procedures, administers medications, documents vital signs, and manages patient education.

Last seen Aug 26, 2026
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LPN | Medical

Regional Health

Rapid City, SD, USA Full-time On-site $26 - $30 / hour

Licensed Practical Nurse (LPN) provides direct and indirect patient care in inpatient and ambulatory dialysis units under RN or physician supervision. Responsibilities include assessment, medication administration, nursing procedures, care planning, patient education, documentation, and mentoring.

Last seen Aug 26, 2026
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LPN | Cardiology Clinic

Regional Health

Rapid City, SD, USA Full-time On-site $25 - $29 / hour

Licensed Practical Nurse (LPN) in the Cardiology Clinic at Monument Health Rapid City Hospital provides direct and indirect patient care in an ambulatory setting. The LPN works under physician or RN supervision, performing nursing procedures, medication administration, vital sign collection, and documentation per clinic standards.

Last seen Aug 26, 2026
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Apprenticeship ~ LPN

Huron Regional Medical Center

Huron,SD,USA Full-time On-site

Huron Regional Medical Center Apprenticeship LPN program rotates the apprentice through 4-6 nursing areas under RN supervision, allowing 2-4 weeks of hands‑on patient care, communication, and care coordination. The role supports direct nursing care for individual clients with defined diagnoses and organizes nursing tasks during each work period.

Last seen Aug 26, 2026
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LPN | Medical

Regional Health

Rapid City, SD, USA Full-time On-site $26 - $30 / hour

The Licensed Practical Nurse (LPN) will provide direct and indirect patient care in inpatient and ambulatory dialysis units at Monument Health Rapid City Hospital. Working under the supervision of physicians or registered nurses, the LPN will conduct focused assessments, administer medications, perform nursing procedures, and document care in accordance with state regulations and hospital policies.

Last seen Aug 26, 2026
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LPN | Medical

Regional Health

Rapid City,SD,USA Full-time $26 - $30 / hour

LPN on the Rapid City Medical team at Monument Health delivers direct and indirect patient care in inpatient and ambulatory dialysis units, collaborating with RNs and physicians to assess, treat, and document patient needs. The role involves medication administration, nursing procedures, patient education, and participation in quality improvement and onboarding.

Last seen Aug 26, 2026
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LPN | Gastroenterology

Regional Health

Rapid City, SD, USA Full-time On-site $25 - $29 / hour

LPN on the Gastroenterology team at Monument Health Rapid City Clinic provides direct patient care in an ambulatory setting, collaborating with physicians and RNs to deliver quality nursing services. The role involves preparing exam areas, documenting vital signs, administering medications, and supporting patient education while adhering to South Dakota Nurse Practice Act standards.

Last seen Aug 26, 2026
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LPN - Gastroenterology Clinic

Sanford Health

Sioux Falls,SD,US Full-time On-site $22 - $30 / hour

GI Team at Sanford Health's newly constructed Gastroenterology Clinic provides patient-centered care across GI subspecialties. The LPN supports the fast‑paced Hepatology team by assessing patients, documenting histories, administering medications and IV therapy, and educating patients and families under RN supervision.

Last seen Aug 26, 2026
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Clinic - LPN | Avera Heart Hospital

Avera Health

Sioux Falls, SD, United States of America Full-time On-site

Clinic LPN at Avera Heart Hospital provides essential nursing support in the cardiology clinic. Responsibilities include entering orders and refilling medications in EMR, delivering patient education, rooming patients, cleaning exam rooms, and assisting cardiology APPs and physicians.

Last seen Aug 26, 2026
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Medical Assistant or LPN | Rheumatology

Regional Health

Rapid City, SD, United States Full-time On-site $20 - $29 / hour

Medical Assistant or LPN at Monument Health Rapid City Clinic provides compassionate patient-focused care in an ambulatory rheumatology setting. The role includes preparing examination areas, completing patient rooming and vital signs, administering and documenting unit dose medications and immunizations, performing EKGs and laboratory testing per CLIA license, ensuring accurate patient record documentation, completing clerical activities and supply maintenance, assisting with scheduling follow-

Last seen Aug 26, 2026
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RN/ LPN or CMA

Community HealthCare Association of the Dakotas

Yankton,SD,USA Full-time On-site

Horizon Health in Yankton, SD provides outpatient nursing care within its community clinic. The role coordinates patient visits, records vitals and history in the EHR, educates patients, and performs nursing tasks such as injections, vaccinations, labs and x‑rays.

Last seen Aug 26, 2026
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RN/LPN/CMA

Community HealthCare Association of the Dakotas

Wessington Springs, SD, USA Full-time On-site

Horizon Health in Wessington Springs, SD seeks an RN, LPN, or CMA to deliver patient-centered care in its outpatient clinic. The role involves coordinating patient visits, performing clinical skills like injections and labs, and providing health education within a collaborative team environment.

Last seen Aug 26, 2026
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LPN | Rheumatology Infusion

Regional Health

Rapid City,SD,USA Full-time $25 - $29 / hour

LPN on the Rheumatology Infusion team at Monument Health Rapid City Clinic delivers direct patient care in the ambulatory setting, collaborating with physicians and RNs to administer medications, perform nursing procedures, and document assessments. The role supports clinic operations by preparing exam areas, managing patient rooming, and assisting with referrals and authorizations.

Last seen Aug 26, 2026
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RN/LPN/CMA

Community HealthCare Association of the Dakotas

Woonsocket, SD, USA Full-time On-site

Horizon Health in Woonsocket, SD seeks an RN, LPN, or CMA to deliver patient-centered care within its outpatient clinic. The role splits duties between front-office coordination and direct nursing tasks, including rooming patients, administering treatments, and managing schedules.

Last seen Aug 26, 2026
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LPN or Medical Assistant - Orthopedics

Sanford Health

Rapid City, SD, United States Full-time On-site $20 - $30 / hour

Urgent Care team at Black Hills Orthopedic Clinic provides fast‑paced orthopedic care in Rapid City. The LPN/Medical Assistant collects patient data, prepares exams, performs point‑of‑care testing, and supports providers across all phases of care.

Last seen Aug 14, 2026
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LPN or Medical Assistant, Endocrinology

Regional Health

Rapid City,SD,USA Full-time On-site

Endocrinology Clinic at Monument Health provides comprehensive outpatient care for patients with hormonal disorders. The LPN or Medical Assistant delivers direct patient care, prepares exam rooms, records vital signs, administers medications and immunizations, performs EKGs and lab tests, and supports scheduling and documentation.

Last seen Aug 26, 2026
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LPN | Cardiology Clinic

Regional Health

Rapid City,SD,USA Full-time On-site $25 - $29 / hour

Cardiology Clinic (Monument Health) provides outpatient cardiac care to the Rapid City community. The LPN delivers direct patient care, prepares exam rooms, records vital signs, administers medications, and supports physicians and RNs in treatment plans.

Last seen Aug 26, 2026
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RN/ LPN or CMA

Community HealthCare Association of the Dakotas

Eagle Butte,SD,USA Full-time On-site

Horizon Health in Eagle Butte, SD provides outpatient clinic care across Eagle Butte, Isabel, Faith, and Bison. The RN/LPN/CMA role coordinates patient visits, records vitals, updates EHR, educates patients, and performs nursing skills such as injections, vaccinations, labs, and x‑rays.

Last seen Aug 26, 2026
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LPN | Primary Care

Regional Health

Deadwood,SD,USA Part-time $25 - $29

LPN on the Primary Care team at Monument Health’s Deadwood Clinic delivers direct patient care under RN supervision, managing medication administration, vital signs, and patient education. The role supports clinic operations by preparing exam rooms, documenting assessments, and coordinating referrals.

Last seen Aug 23, 2026
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Licensed Practical Nurse Jobs in South Dakota: FAQ

How many Licensed Practical Nurse jobs in South Dakota are open right now?

201 Licensed Practical Nurse jobs in South Dakota are live on NextGig, all seen active within the last 45 days. The list refreshes daily as new roles are posted and filled ones drop off.

Which companies are hiring for Licensed Practical Nurse jobs in South Dakota?

Employers with current openings include Regional Health, Huron Regional Medical Center, Sanford Health, Avera Health, Community HealthCare Association of the Dakotas. Every listing links straight to the employer's application page.

What do Licensed Practical Nurse jobs in South Dakota pay?

13 of the 20 newest listings disclose pay, for example $25 - $29 / hour at Regional Health, $25 - $29 / hour at Regional Health, $26 - $30 / hour at Regional Health. Open a listing for the full compensation details.