Nurse Jobs in South Dakota, United States

755 jobs available

Find Nurse opportunities in South Dakota, United States. Browse 755 open positions from top employers in the area.

Showing 20 of 755 jobs

Registered Nurse (RN) or Licensed Practical Nurse (LPN) | New Grad | Extended Care NH Nurse

Avera Health

Sioux Falls, South Dakota, United States Full-time On-site $24 - $48 / hour

Registered Nurse (RN) or Licensed Practical Nurse (LPN) – New Grad – Extended Care NH Nurse at Avera Prince of Peace‑Skilled Nursing. This role invites recent nursing graduates to begin a career in a multidisciplinary team that values compassion, hospitality, and stewardship.

Last seen Oct 9, 2026
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Registered Nurse (RN) - Visiting Nurse | Home Hospice

Avera Health

Sioux Falls, South Dakota, United States Full-time On-site $31 - $46 / hour

Avera at Home Hospice team provides compassionate home-based hospice care in Sioux Falls. The Registered Nurse delivers comprehensive nursing assessments, creates individualized care plans, and coordinates with families and providers to ensure quality end-of-life support.

Last seen Sep 28, 2026
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Nursing Assistant or Certified Nursing Assistant | Long Term Care

Avera Health

Parkston, South Dakota, United States Part-time On-site $20 - $26 / hour

St. Benedict Health Center nursing team provides compassionate care to long‑term residents. The Nursing Assistant supports daily living activities, monitors vital signs, and assists with basic medical tasks while collaborating with nursing staff.

Last seen Oct 11, 2026
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Nursing Assistant or Certified Nursing Assistant

Avera Health

Parkston, South Dakota, United States Part-time On-site $20 - $26 / hour

Long Term Care at St. Benedict Health Center provides compassionate daily living support for residents in a skilled nursing facility. The Nursing Assistant assists with activities of daily living, vital sign monitoring, documentation, and basic medical care under nursing supervision.

Last seen Oct 11, 2026
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Nurse Manager - RN - Gynecologic Oncology & Nurse Navigator

Sanford Health

Sioux Falls, South Dakota, United States Full-time

The Nurse Manager - RN - Gynecologic Oncology & Nurse Navigator at Sanford Health manages day-to-day operations for nursing staff and nursing activities for outpatient departments, including patient care, record keeping, and personnel issues. This role reports within the outpatient setting, supports the nursing staff in performing clinical roles such as patient educator, caregiver, counsellor, consultant, and patient advocate, and acts as a liaison between nursing, other disciplines, and adminis

Last seen Oct 11, 2026
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Registered Nurse (RN) or Licensed Practical Nurse (LPN) | Long Term Care

Avera Health

Parkston, SD Full-time $32 - $48 / hour

Avera St Benedict Nursing Home in Parkston, SD seeks a Registered Nurse (RN) or Licensed Practical Nurse (LPN) for a full-time night shift role in long-term care. The nurse delivers comprehensive resident care by developing nursing diagnoses, establishing care objectives, defining interventions, and providing physical, emotional, psychological, and spiritual support to residents, families, and friends.

Last seen Oct 11, 2026
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Registered Nurse (RN) or Licensed Practical Nurse (LPN) | Long Term Care

Avera Health

Parkston, SD Full-time On-site $24 - $48 / hour

Registered Nurse or Licensed Practical Nurse at Avera St Benedict Nursing Home. Provide nursing care, assessment, documentation, care planning, medication administration, infection control, equipment maintenance, supply management, admissions/discharges, workflow coordination, and competence maintenance.

Last seen Oct 11, 2026
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Certified Nursing Assistant, GHC Nursing Home

Avera Health

Gregory, South Dakota, United States Part-time On-site $20 - $26 / hour

Avera Rosebud Country Care Center provides compassionate skilled nursing care in Gregory, SD. As a Certified Nursing Assistant you will deliver direct personal care, assist with daily living activities, monitor vital signs, and support the nursing staff in a rotating 8‑hour shift schedule. Gregory, SD, On-site, 3 days onsite per week, relocation assistance available.

Last seen Oct 11, 2026
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Registered Nurse or Licensed Practical Nurse or Medical Assistant, Float

Avera Health

Harrisburg, South Dakota, United States Part-time On-site $20 - $41 / hour

Avera Health's Tea Clinic Float team provides compassionate nursing and clinical support across its Tea, Harrisburg, and Salem locations in South Dakota. The role delivers direct patient care, administers medications, prepares equipment, and coordinates clinic flow while adapting to the needs of each site.

Last seen Oct 11, 2026
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Registered Nurse (RN) | Oncology Outpatient Clinical Nurse Educator

Avera Health

Pierre, SD Full-time $29 - $43 / hour

The Oncology Outpatient Clinical Nurse Educator at Avera Cancer Institute (Sioux Falls, SD, with additional locations in Pierre, Yankton, Aberdeen, and Mitchell) is a full-time, day-shift role focused on staff development and evidence-based clinical practice. The educator serves as a consultant, facilitator, change agent, and leader who assesses, plans, implements, and evaluates competency assessment, continuing education, and leadership development for nursing staff.

Last seen Oct 11, 2026
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Registered Nurse (RN) or Licensed Practical Nurse (LPN) or Medical Assistant

Avera Health

Sioux Falls, South Dakota, United States Full-time On-site $20 - $41 / hour

Avera 7th Avenue Clinic team delivers primary nursing care and supports multidisciplinary providers in Sioux Falls. The role provides direct patient care, administers medications, coordinates clinic flow, and educates patients and families.

Last seen Oct 6, 2026
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Registered Nurse (RN) or Licensed Practical Nurse (LPN) | Long Term Care

Avera Health

Aberdeen, South Dakota, United States Full-time On-site $24 - $48 / hour

Registered Nurse (RN) or Licensed Practical Nurse (LPN) position at Avera Mother Joseph Manor Retirement Community in Aberdeen, SD. The role provides comprehensive nursing care to residents, including assessment, medication administration, care planning, and coordination with interdisciplinary team. Nurses work rotating shifts covering days, evenings, nights, weekends, and holidays, with 72-hour cycles every two weeks.

Last seen Oct 11, 2026
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Registered Nurse (RN) or Licensed Practical Nurse (LPN) | Behavioral Health Unit

Avera Health

Aberdeen, South Dakota, United States Full-time On-site $24 - $46 / hour

Registered Nurse (RN) or Licensed Practical Nurse (LPN) needed for a Behavioral Health Unit at Avera St. Luke's Hospital in Aberdeen, SD. The role involves patient assessment, care plan development, medication administration, documentation, infection control, equipment and supply management, and interprofessional communication. Shift is rotating days, evenings, nights, weekends, and holidays.

Last seen Oct 11, 2026
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Registered Nurse (RN) or Licensed Practical Nurse (LPN | Long Term Care

Avera Health

Yankton, South Dakota, United States Part-time On-site $24 - $48 / hour

Registered Nurse (RN) or Licensed Practical Nurse (LPN) position at Avera Majestic Bluffs/Avera Sister James Care Center in Yankton, SD. Night shift (6pm-6:30am) part‑time, 20 hours per two weeks. Provide comprehensive nursing care: assess residents, develop care plans, administer medications, educate families, coordinate with physicians and interdisciplinary team, maintain infection control, document care, troubleshoot equipment, manage supplies, and support residents’ physical, emotional, psyc

Last seen Oct 11, 2026
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Registered Nurse (RN) or Licensed Practical Nurse (LPN) | Behavioral Health Adolescent Unit

Avera Health

Sioux Falls, South Dakota, United States Full-time On-site $24 - $48 / hour

Registered Nurse (RN) or Licensed Practical Nurse (LPN) in Behavioral Health Adolescent Unit. Provide patient care, develop nursing care plans, teach patients and families, evaluate outcomes, maintain infection control, document care, manage equipment and supplies, and uphold Avera’s values.

Last seen Oct 11, 2026
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Care Manager Nurse (Registered Nurse)

Great Plains Tribal Leaders Health Board

Rapid City, South Dakota, United States Full-time On-site $36 - $45 / hour

Oyate Health Center team provides comprehensive outpatient and urgent care for American Indian communities, focusing on whole-patient health and seamless care continuity. The Care Manager Nurse assesses, plans, and coordinates individualized care plans, manages high‑risk patient registries, and collaborates with providers and external programs to reduce hospital and ER utilization.

Last seen Oct 11, 2026
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Registered Nurse (RN) or Licensed Practical Nurse (LPN) or Medical Assistant | McGreevy 7th Ave

Avera Health

Sioux Falls, South Dakota, United States Full-time On-site $20 - $41 / hour

Avera Health Clinic team delivers compassionate primary care to the Sioux Falls community. The role provides professional nursing care, medication administration, patient assessments, and supports clinic operations while collaborating with physicians and staff.

Last seen Oct 6, 2026
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Registered Nurse / Licensed Practical Nurse

Brookings Health System

Brookings, South Dakota, United States Full-time On-site $24 - $45 / hour

The Neighborhoods at Brookview team at Brookings Health System provides compassionate, resident‑focused care in a long‑term care setting. Registered Nurses and Licensed Practical Nurses lead daily clinical activities, coordinate with interdisciplinary staff, and ensure individualized wellbeing for each resident during night shifts.

Last seen Oct 9, 2026
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Registered Nurse, Licensed Practical Nurse

Avera Health

Sioux Falls, South Dakota, United States Part-time On-site $22 - $41 / hour

Avera Health Clinic team provides compassionate primary nursing care in a multidisciplinary setting. The RN/LPN delivers patient assessments, administers medications, coordinates clinic flow, and supports providers during procedures, Monday‑Friday 8 am‑5 pm.

Last seen Oct 11, 2026
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Registered Nurse (RN) or Licensed Practical Nurse (LPN) | Long Term Care

Avera Health

Aberdeen, South Dakota, United States Part-time $24 - $34 / hour

Avera Mother Joseph Manor Retirement Community’s Nursing Team delivers compassionate, resident‑centered care in a long‑term setting. The LPN role performs assessments, medication administration via Pyxis, care planning, and collaborates with RN and physicians using SBAR.

Last seen Oct 11, 2026
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Nurse Jobs in South Dakota: FAQ

How many Nurse jobs in South Dakota are open right now?

755 Nurse jobs in South Dakota are live on NextGig, all seen active within the last 45 days. The list refreshes daily as new roles are posted and filled ones drop off.

Which companies are hiring for Nurse jobs in South Dakota?

Employers with current openings include Avera Health, Sanford Health, Great Plains Tribal Leaders Health Board, Brookings Health System. Every listing links straight to the employer's application page.

What do Nurse jobs in South Dakota pay?

19 of the 20 newest listings disclose pay, for example $24 - $48 / hour at Avera Health, $31 - $46 / hour at Avera Health, $20 - $26 / hour at Avera Health. Open a listing for the full compensation details.