Registered Nurse Jobs in South Dakota, United States

793 jobs available

Find Registered Nurse opportunities in South Dakota, United States. Browse 793 open positions from top employers in the area.

Showing 20 of 793 jobs

Registered Nurse (RN) - Visiting Nurse

Avera Health

Mitchell,SD,United States Full-time On-site $31 - $46 / hour

Avera at Home Visiting Nurse team provides compassionate in‑home nursing care to patients, ensuring safe and effective treatment in the community. The Registered Nurse collects health data, assesses needs, develops and implements individualized care plans, and evaluates outcomes while collaborating with patients, families, and providers.

Last seen Aug 24, 2026
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Care Manager Nurse (Registered Nurse)

Great Plains Tribal Leaders Health Board

Rapid City, SD, US Full-time On-site $36 - $45 / hour

Oyate Health Center team provides comprehensive outpatient and urgent care for American Indian communities, focusing on whole-patient health and seamless care continuity. The Care Manager Nurse assesses, plans, and coordinates individualized care plans, manages high‑risk patient registries, and collaborates with providers and external programs to reduce hospital and ER utilization.

Last seen Aug 26, 2026
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Registered Nurse (RN) or Licensed Practical Nurse (LPN)

Avera Health

Sioux Falls, SD, United States Full-time On-site $22 - $41 / hour

Avera Family Medicine Center Dawley Farm clinic delivers pediatric care with a compassionate multidisciplinary team. The RN/LPN provides direct nursing care, administers medications, prepares equipment, and coordinates patient flow in the clinic.

Last seen Aug 17, 2026
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Registered Nurse (RN) - Visiting Nurse | Home Hospice

Avera Health

Sioux Falls,SD,United States Full-time On-site $31 - $46 / hour

Avera at Home Hospice team provides compassionate home-based hospice care in Sioux Falls. The Registered Nurse delivers comprehensive nursing assessments, creates individualized care plans, and coordinates with families and providers to ensure quality end-of-life support.

Last seen Aug 26, 2026
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Registered Nurse (RN) Visit Nurse | Homecare Milbank PRN

Avera Health

Milbank,SD,United States Part-time On-site $31 - $46 / hour

Avera at Home provides compassionate in‑home care for patients across South Dakota. The Registered Nurse Visit Nurse delivers comprehensive nursing assessments, develops individualized care plans, and implements interventions for patients in their homes.

Last seen Aug 26, 2026
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Registered Nurse (RN) | Licensed Practical Nurse (LPN) | Brookings Clinic

Avera Health

Brookings, SD Full-time $22 - $41 / hour

Avera Specialty Care, a department of Brookings Health System in Brookings, SD, seeks a Registered Nurse (RN) or Licensed Practical Nurse (LPN) to join a multidisciplinary team advancing patient care. The role provides professional nursing care in an outpatient clinic setting, administering medications, assisting providers during procedures, screening patients, managing appointment flow, and educating patients and families.

Last seen Aug 26, 2026
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Registered Nurse (RN) or Licensed Practical Nurse (LPN) | Med Surg

Avera Health

Wessington Springs, SD, United States of America Part-time On-site $24 - $48 / hour

Registered Nurse or Licensed Practical Nurse needed for Med Surg unit at Avera Weskota Memorial Hospital in Wessington Springs, SD. Night shift (7 pm–7 am) with 48‑hour/2‑week schedule, including weekends and every third holiday. Pay $24.50–$48.50/hr with shift differentials ($3 / hour 7 pm–7 am, $2 / hour weekends, $5 / hour weekend nights).

Last seen Aug 26, 2026
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Registered Nurse (RN) or Licensed Practical Nurse (LPN) | Long Term Care

Avera Health

Parkston, SD Full-time On-site $24 - $48 / hour

Registered Nurse or Licensed Practical Nurse at Avera St Benedict Nursing Home. Provide nursing care, assessment, documentation, care planning, medication administration, infection control, equipment maintenance, supply management, admissions/discharges, workflow coordination, and competence maintenance.

Last seen Aug 24, 2026
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Registered Nurse / Licensed Practical Nurse

Brookings Health System

Brookings, SD, United States Full-time On-site $24 - $45 / hour

The Neighborhoods at Brookview team at Brookings Health System provides compassionate, resident‑focused care in a long‑term care setting. Registered Nurses and Licensed Practical Nurses lead daily clinical activities, coordinate with interdisciplinary staff, and ensure individualized wellbeing for each resident during night shifts.

Last seen Aug 26, 2026
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Registered Nurse, Licensed Practical Nurse

Avera Health

Sioux Falls, SD, United States Part-time On-site $22 - $41 / hour

Avera Health Clinic team provides compassionate primary nursing care in a multidisciplinary setting. The RN/LPN delivers patient assessments, administers medications, coordinates clinic flow, and supports providers during procedures, Monday‑Friday 8 am‑5 pm.

Last seen Aug 26, 2026
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Registered Nurse (RN) or Licensed Practical Nurse | Cancer Institute Float Pool

Avera Health

Sioux Falls, SD Part-time $22 - $41 / hour

The Registered Nurse (RN) or Licensed Practical Nurse (LPN) role at Avera's Cancer Institute Float Pool in Sioux Falls, SD, delivers professional nursing care under provider direction within a part-time family practice float position on the day shift. Day-to-day duties include administering medications and treatments, coordinating clinic patient care, preparing equipment and assisting providers during procedures, screening patients and taking vitals, responding to patient calls, educating patien

Last seen Aug 26, 2026
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Registered Nurse (RN) or Licensed Practical Nurse (LPN) or Medical Assistant

Avera Health

Sioux Falls,SD,United States Full-time On-site $20 - $41 / hour

Avera 7th Avenue Clinic team delivers primary nursing care and supports multidisciplinary providers in Sioux Falls. The role provides direct patient care, administers medications, coordinates clinic flow, and educates patients and families.

Last seen Aug 26, 2026
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Registered Nurse or Licensed Practical Nurse or Medical Assistant, Float

Avera Health

Harrisburg,SD,United States Part-time On-site $20 - $41 / hour

Avera Health's Tea Clinic Float team provides compassionate nursing and clinical support across its Tea, Harrisburg, and Salem locations in South Dakota. The role delivers direct patient care, administers medications, prepares equipment, and coordinates clinic flow while adapting to the needs of each site.

Last seen Aug 26, 2026
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Registered Nurse or Licensed Practical Nurse, Long Term Care

Avera Health

Yankton, SD, United States Part-time On-site $24 - $48 / hour

Long Term Care Nursing at Avera Health delivers compassionate resident care in a multidisciplinary setting. Provides direct nursing services, develops care plans, educates families, and coordinates with physicians and staff to ensure safe, holistic support for long‑term care residents.

Last seen Aug 26, 2026
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Registered Nurse (RN) or Licensed Practical Nurse (LPN) | Pulmonary Clinic

Avera Health

Sioux Falls, SD, United States of America Full-time On-site $22 - $41 / hour

Provide professional nursing care in Avera Medical Group Pulmonary & Sleep Medicine clinic. Coordinate with physicians and multidisciplinary team to deliver patient-centered care.

Last seen Aug 26, 2026
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Registered Nurse, Licensed Practical Nurse, 69th and Western Clinic

Avera Health

Sioux Falls,SD,US Full-time On-site $22 - $41 / hour

Avera 69th & Western Clinic provides primary care services to the community, focusing on compassionate patient care. The Registered Nurse/Licensed Practical Nurse delivers professional nursing care, administers medications, coordinates clinic flow, and educates patients and families.

Last seen Aug 26, 2026
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Registered Nurse (RN) or Licensed Practical Nurse (LPN) | New Grad | Extended Care NH Nurse

Avera Health

Sioux Falls, SD, United States of America Full-time On-site $24 - $48 / hour

Registered Nurse (RN) or Licensed Practical Nurse (LPN) – New Grad – Extended Care NH Nurse at Avera Prince of Peace‑Skilled Nursing. This role invites recent nursing graduates to begin a career in a multidisciplinary team that values compassion, hospitality, and stewardship.

Last seen Aug 26, 2026
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Registered Nurse (RN) or Licensed Practical Nurse (LPN) | Behavioral Health Unit

Avera Health

Aberdeen, SD, United States Full-time On-site $24 - $46 / hour

Registered Nurse (RN) or Licensed Practical Nurse (LPN) needed for a Behavioral Health Unit at Avera St. Luke's Hospital in Aberdeen, SD. The role involves patient assessment, care plan development, medication administration, documentation, infection control, equipment and supply management, and interprofessional communication. Shift is rotating days, evenings, nights, weekends, and holidays.

Last seen Aug 26, 2026
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Registered Nurse (RN) or Licensed Practical Nurse (LPN) | Long Term Care

Avera Health

Aberdeen, SD, United States of America Full-time On-site $24 - $48 / hour

Registered Nurse (RN) or Licensed Practical Nurse (LPN) position at Avera Mother Joseph Manor Retirement Community in Aberdeen, SD. The role provides comprehensive nursing care to residents, including assessment, medication administration, care planning, and coordination with interdisciplinary team. Nurses work rotating shifts covering days, evenings, nights, weekends, and holidays, with 72-hour cycles every two weeks.

Last seen Aug 26, 2026
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Registered Nurse (RN) or Licensed Practical Nurse (LPN) | Transitional Care Unit

Avera Health

Sioux Falls, SD, United States Full-time On-site $24 - $48 / hour

Transitional Care Unit at Avera Health provides compassionate, multidisciplinary nursing care for residents transitioning between care settings. The role delivers comprehensive patient assessments, develops individualized care plans, and coordinates with physicians and support staff to ensure safe, holistic care.

Last seen Aug 26, 2026
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Registered Nurse Jobs in South Dakota: FAQ

How many Registered Nurse jobs in South Dakota are open right now?

793 Registered Nurse jobs in South Dakota are live on NextGig, all seen active within the last 45 days. The list refreshes daily as new roles are posted and filled ones drop off.

Which companies are hiring for Registered Nurse jobs in South Dakota?

Employers with current openings include Avera Health, Great Plains Tribal Leaders Health Board, Brookings Health System. Every listing links straight to the employer's application page.

What do Registered Nurse jobs in South Dakota pay?

20 of the 20 newest listings disclose pay, for example $31 - $46 / hour at Avera Health, $36 - $45 / hour at Great Plains Tribal Leaders Health Board, $22 - $41 / hour at Avera Health. Open a listing for the full compensation details.