Registered Nurse Jobs in South Dakota, United States

Avera at Home Hospice team provides compassionate home-based hospice care in Sioux Falls. The Registered Nurse delivers comprehensive nursing assessments, creates individualized care plans, and coordinates with families and providers to ensure quality end-of-life support.

Registered Nurse (RN) or Licensed Practical Nurse (LPN) – New Grad – Extended Care NH Nurse at Avera Prince of Peace‑Skilled Nursing. This role invites recent nursing graduates to begin a career in a multidisciplinary team that values compassion, hospitality, and stewardship.

Registered Nurse or Licensed Practical Nurse at Avera St Benedict Nursing Home. Provide nursing care, assessment, documentation, care planning, medication administration, infection control, equipment maintenance, supply management, admissions/discharges, workflow coordination, and competence maintenance.

Avera St Benedict Nursing Home in Parkston, SD seeks a Registered Nurse (RN) or Licensed Practical Nurse (LPN) for a full-time night shift role in long-term care. The nurse delivers comprehensive resident care by developing nursing diagnoses, establishing care objectives, defining interventions, and providing physical, emotional, psychological, and spiritual support to residents, families, and friends.

Oyate Health Center team provides comprehensive outpatient and urgent care for American Indian communities, focusing on whole-patient health and seamless care continuity. The Care Manager Nurse assesses, plans, and coordinates individualized care plans, manages high‑risk patient registries, and collaborates with providers and external programs to reduce hospital and ER utilization.

The Oncology Outpatient Clinical Nurse Educator at Avera Cancer Institute (Sioux Falls, SD, with additional locations in Pierre, Yankton, Aberdeen, and Mitchell) is a full-time, day-shift role focused on staff development and evidence-based clinical practice. The educator serves as a consultant, facilitator, change agent, and leader who assesses, plans, implements, and evaluates competency assessment, continuing education, and leadership development for nursing staff.

Avera Health's Tea Clinic Float team provides compassionate nursing and clinical support across its Tea, Harrisburg, and Salem locations in South Dakota. The role delivers direct patient care, administers medications, prepares equipment, and coordinates clinic flow while adapting to the needs of each site.

Avera 7th Avenue Clinic team delivers primary nursing care and supports multidisciplinary providers in Sioux Falls. The role provides direct patient care, administers medications, coordinates clinic flow, and educates patients and families.

Registered Nurse (RN) or Licensed Practical Nurse (LPN) position at Avera Mother Joseph Manor Retirement Community in Aberdeen, SD. The role provides comprehensive nursing care to residents, including assessment, medication administration, care planning, and coordination with interdisciplinary team. Nurses work rotating shifts covering days, evenings, nights, weekends, and holidays, with 72-hour cycles every two weeks.

Registered Nurse (RN) or Licensed Practical Nurse (LPN) needed for a Behavioral Health Unit at Avera St. Luke's Hospital in Aberdeen, SD. The role involves patient assessment, care plan development, medication administration, documentation, infection control, equipment and supply management, and interprofessional communication. Shift is rotating days, evenings, nights, weekends, and holidays.

Registered Nurse (RN) or Licensed Practical Nurse (LPN) position at Avera Majestic Bluffs/Avera Sister James Care Center in Yankton, SD. Night shift (6pm-6:30am) part‑time, 20 hours per two weeks. Provide comprehensive nursing care: assess residents, develop care plans, administer medications, educate families, coordinate with physicians and interdisciplinary team, maintain infection control, document care, troubleshoot equipment, manage supplies, and support residents’ physical, emotional, psyc

The Neighborhoods at Brookview team at Brookings Health System provides compassionate, resident‑focused care in a long‑term care setting. Registered Nurses and Licensed Practical Nurses lead daily clinical activities, coordinate with interdisciplinary staff, and ensure individualized wellbeing for each resident during night shifts.

Avera Health Clinic team provides compassionate primary nursing care in a multidisciplinary setting. The RN/LPN delivers patient assessments, administers medications, coordinates clinic flow, and supports providers during procedures, Monday‑Friday 8 am‑5 pm.

Registered Nurse (RN) or Licensed Practical Nurse (LPN) in Behavioral Health Adolescent Unit. Provide patient care, develop nursing care plans, teach patients and families, evaluate outcomes, maintain infection control, document care, manage equipment and supplies, and uphold Avera’s values.

Avera Health Clinic team delivers compassionate primary care to the Sioux Falls community. The role provides professional nursing care, medication administration, patient assessments, and supports clinic operations while collaborating with physicians and staff.

Registered Nurse or Licensed Practical Nurse needed for Med Surg unit at Avera Weskota Memorial Hospital in Wessington Springs, SD. Night shift (7 pm–7 am) with 48‑hour/2‑week schedule, including weekends and every third holiday. Pay $24.50–$48.50/hr with shift differentials ($3 / hour 7 pm–7 am, $2 / hour weekends, $5 / hour weekend nights).

Avera Mother Joseph Manor Retirement Community’s Nursing Team delivers compassionate, resident‑centered care in a long‑term setting. The LPN role performs assessments, medication administration via Pyxis, care planning, and collaborates with RN and physicians using SBAR.

The Registered Nurse (RN) or Licensed Practical Nurse (LPN) role at Avera's Cancer Institute Float Pool in Sioux Falls, SD, delivers professional nursing care under provider direction within a part-time family practice float position on the day shift. Day-to-day duties include administering medications and treatments, coordinating clinic patient care, preparing equipment and assisting providers during procedures, screening patients and taking vitals, responding to patient calls, educating patien

Avera Pierre Clinic seeks a Registered Nurse (RN), Licensed Practical Nurse (LPN), or Medical Assistant (MA) to serve as the primary nurse for Kim Haines, CNP in a family practice clinic in Pierre, SD. The role delivers professional nursing care under provider direction, including medication administration, patient screening, vitals, documentation, patient education, appointment coordination, and occasional acute care rotation on Friday evenings/Saturday mornings. Work schedule is primarily days

Avera Pierre Clinic seeks a Registered Nurse (RN), Licensed Practical Nurse (LPN), or Medical Assistant (MA) to serve as the primary nurse for an APP on Dr. Strasburg's family practice team in Pierre, SD. The role delivers professional nursing care under provider direction, including administering medications, assisting with procedures, coordinating patient care, and educating patients and families. Work is primarily days with possible weekends, evenings, and holidays, following an 8:00am-5:00pm